A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control
نویسندگان
چکیده
منابع مشابه
A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control
How cells control the overall size and growth of membrane-bound organelles is an important unanswered question of cell biology. Fission yeast cells maintain a nuclear size proportional to cellular size, resulting in a constant ratio between nuclear and cellular volumes (N/C ratio). We have conducted a genome-wide visual screen of a fission yeast gene deletion collection for viable mutants alter...
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ژورنال
عنوان ژورنال: PLOS Genetics
سال: 2017
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1006767